At least, that's what recent history tells us. Since the NFL started playing 17 games in 2021, the 47 teams that lost their opener made the playoffs just 13 times, 27.7% of the time.

And it gets worse! The Colts were a 2.5-point underdog Sunday, the 25 underdogs that lost their opener including just five teams that made the playoffs, a 20% chance.

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That's a small sample size and, of course, none of those teams had Anthony Richardson at quarterback. There's still a chance for the Colts to be successful. Here are the five teams that made the playoffs: